(2018). 19, 401–405. The intestinal microbiome protects against invasion by exogenous pathogens directly, by competitively binding to epithelial cells, and indirectly, by triggering immunoprotective responses (Boyle et al., 2011; Kosiewicz et al., 2014). Food Sci. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. doi: 10.7241/ourd.20124.71. Trends in Microbiology presents the Microbiologist’s Field Guide, a quick-glance reference pamphlet showcasing need-to-know information about key organisms in infection and the environment! Muraro, A., Lemanske, R. F., Hellings, P. W., Akdis, C. A., Bieber, T., Casale, T. B., et al. doi: 10.1038/jid.2011.375, Lynn, D., Umari, T., Dunnick, C., and Dellavalle, R. (2016). doi: 10.1038/nri1373, Mari, N. L., Simão, A. N. C., and Dichi, I. Skin manifestations of inflammatory bowel disease. In a third study, maternal and infant supplementation with Bifidobacterium breve M-16V and Bifidobacterium longum BB536 further supported the preventative effect of probiotics in AD (Enomoto et al., 2014). Given the gut microbiome’s integral role in immune development and homeostasis, probiotics may be useful in both the prevention and treatment of allergic disorders including AD via microbial, epithelial, and immune effects. doi: 10.1016/j.jfda.2016.06.003, Clarke, T. B., Davis, K. M., Lysenko, E. S., Zhou, A. Y., Yu, Y., and Weiser, J. N. (2010). Microbiol. Wiegand, C., Raschke, C., and Elsner, P. (2016). Gut microbiota influence the pathophysiology of acne via cross talk between intestinal commensal bacteria and the mTOR pathway (Noureldein and Eid, 2018). Frontiers in Microbiology is a leading journal in its field, publishing rigorously peer-reviewed research across the entire spectrum of microbiology. “CD1 expression on antigen-presenting cells,” in T Cell Activation by CD1 and Lipid Antigens. Allergy Immunol. Frontiers in Microbiology is a leading journal in its field, publishing rigorously peer-reviewed research across the entire spectrum of microbiology. Oral probiotic control skin inflammation by acting on both effector and regulatory T cells. The Infectious Diseases section within Frontiers in Microbiology provides a publication platform for high-quality research on infectious diseases, which encompass the broad spectrum of host-microbe interaction from dysbiotic conditions … “Skin aging: a brief summary of characteristic changes,” in Textbook of Aging Skin, eds M. A. Farage, K. W. Miller, and H. I. Maibach (Berlin: springer). doi: 10.1016/j.jaci.2017.02.007, Ipci, K., Altıntoprak, N., Muluk, N. B., Senturk, M., and Cingi, C. (2017). Studies have sought to demonstrate how modulation of the gut microbiome can influence immune signaling pathways in a way that counteracts UV damage. J. Immunol. Immunol. 24, 1583–1591. Nutr. Dairy Sci. doi: 10.1097/MOG.0000000000000151, Frei, R., Lauener, R. P., Crameri, R., and O’Mahony, L. (2012). (2014). Through complex immune mechanisms, the influence of the gut microbiome extends to involve distant organ systems including the skin. Acne vulgaris: nutritional factors may be influencing psychological sequelae. Though long-term dietary habits shape bacterial composition, dramatic modulation of diet over the short term can rapidly alter gut bacteria as well. J. Mol. 78, 79–82. Frontiers is my first choice in preparing my essay for publishment.I sent my manuscript to Frontiers rather than any other journal.I like it because of its high efficience and enthusiasm.I read a lot of articles from frontiers,which are very nice.This is a very professional journal which reports the newest scientific progress.Microbiology is my major and I often read this journal of microbiology.I think this is a very nice and reliable journal.All best wishes go to Frontiers. doi: 10.1016/j.jaci.2014.12.013, Kim, H., Kim, H. Y., Lee, S., Seo, J., Lee, E., and Hong, S. (2013). doi: 10.1136/bmj.f2634, Dawson, L. F., Donahue, E. H., Cartman, S. T., Barton, R. H., Bundy, J., McNerney, R., et al. Reduced local and systemic immune tolerance resulting from an altered gut microbiome may help explain the observed rise of both autoimmune and atopic disease observed in the western world (Maslowski et al., 2009; Agrawal et al., 2011; Purchiaroni et al., 2013; Seite and Bieber, 2015; Johnson and Ownby, 2017). Frontiers in Immunology is a leading journal in its field, publishing rigorously peer-reviewed research across basic, translational and clinical immunology. Probiotic supplementation, the administration of live beneficial gut bacteria, has a promising potential role in the prevention and management of various skin conditions (Krutmann, 2009; Hill et al., 2014; Farris, 2016; Grant and Baker, 2017; Sánchez et al., 2017; Sarao and Arora, 2017). You, G. E., Jung, B. J., Kim, H. R., Kim, H. G., Kim, T. R., and Chung, D. K. (2013). Gut microbiota and mTOR signaling: insight on a new pathophysiological interaction. doi: 10.1038/nature10228, Fabbrocini, G., Bertona, M., Picazo,Ó., Pareja-Galeano, H., Monfrecola, G., and Emanuele, E. (2016). With an Impact Factor of 4.300, the journal is the 5th most cited open-access journal in the Microbiology category (Figure 2). PLoS One 8:e78898. doi: 10.1136/gut.2008.165886, Cavinato, M., and Jansen-Dürr, P. (2017).